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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: CENPA All Species: 18.72
Human Site: S7 Identified Species: 29.42
UniProt: P49450 Number Species: 14
    Phosphosite Substitution
    Charge Score: -0.07
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P49450 NP_001035891.1 140 15991 S7 _ M G P R R R S R K P E A P R
Chimpanzee Pan troglodytes XP_515346 138 15774 S7 _ M G P R R R S R K P E A P R
Rhesus Macaque Macaca mulatta XP_001087306 138 15765 S7 _ M G P R R R S R K P E A P R
Dog Lupus familis XP_532899 135 15196 P7 _ M G P R R K P E V P K R R P
Cat Felis silvestris
Mouse Mus musculus O35216 134 15491 P7 _ M G P R R K P Q T P R R R P
Rat Rattus norvegicus P84245 136 15309 T7 _ M A R T K Q T A R K S T G G
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001509693 121 13998 P11 G V G E G R A P R P T P S P R
Chicken Gallus gallus Q6XXM1 131 15224 S8 M P R P K P R S P R R R G R P
Frog Xenopus laevis Q569M3 150 17325 P16 S R R K S R P P R R V S P P L
Zebra Danio Brachydanio rerio Q803H4 145 16662 K9 P R H T S A H K R K P S T P R
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster P02299 136 15370 T7 _ M A R T K Q T A R K S T G G
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans Q10453 136 15323 T7 _ M A R T K Q T A R K S T G G
Sea Urchin Strong. purpuratus P06352 136 15483 T7 _ M A R T K Q T A R K S T G G
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q9LR02 136 15384 T7 _ M A R T K Q T A R K S H G G
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa Q7RXR3 155 17319 A13 G G V T K S K A V S K K A A A
Conservation
Percent
Protein Identity: 100 98.5 92.8 77.1 N.A. 70 45 N.A. 60 58.5 54.6 55.1 N.A. 44.2 N.A. 44.2 44.2
Protein Similarity: 100 98.5 93.5 83.5 N.A. 80.7 56.4 N.A. 72.8 71.4 67.3 64.8 N.A. 57.1 N.A. 56.4 57.1
P-Site Identity: 100 100 100 42.8 N.A. 42.8 7.1 N.A. 33.3 20 20 33.3 N.A. 7.1 N.A. 7.1 7.1
P-Site Similarity: 100 100 100 57.1 N.A. 57.1 35.7 N.A. 53.3 33.3 26.6 33.3 N.A. 35.7 N.A. 35.7 35.7
Percent
Protein Identity: N.A. N.A. N.A. 47.8 N.A. 47.7
Protein Similarity: N.A. N.A. N.A. 58.5 N.A. 61.9
P-Site Identity: N.A. N.A. N.A. 7.1 N.A. 6.6
P-Site Similarity: N.A. N.A. N.A. 35.7 N.A. 40
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 34 0 0 7 7 7 34 0 0 0 27 7 7 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % D
% Glu: 0 0 0 7 0 0 0 0 7 0 0 20 0 0 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 14 7 40 0 7 0 0 0 0 0 0 0 7 34 34 % G
% His: 0 0 7 0 0 0 7 0 0 0 0 0 7 0 0 % H
% Ile: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % I
% Lys: 0 0 0 7 14 34 20 7 0 27 40 14 0 0 0 % K
% Leu: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 7 % L
% Met: 7 67 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % N
% Pro: 7 7 0 40 0 7 7 27 7 7 40 7 7 40 20 % P
% Gln: 0 0 0 0 0 0 34 0 7 0 0 0 0 0 0 % Q
% Arg: 0 14 14 34 34 47 27 0 40 47 7 14 14 20 34 % R
% Ser: 7 0 0 0 14 7 0 27 0 7 0 47 7 0 0 % S
% Thr: 0 0 0 14 34 0 0 34 0 7 7 0 34 0 0 % T
% Val: 0 7 7 0 0 0 0 0 7 7 7 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 67 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _